Jubilance PMS is a nutritional supplement marketed to help relieve emotional and mood-related symptoms of Premenstrual Syndrome (PMS), such as anxiety, stress, irritability, gloomy mood, and mood swings. It’s not a drug or hormonal medication- rather, it is a non-hormonal, over-the-counter daily capsule.
What It Is?
Jubilance is a daily PMS relief supplement containing two main ingredients:
Oxaloacetate (OAA): a compound include in cellular metabolism that may help support stable brain glucose levels, which is thought to influence emotional symptoms of PMS.
Vitamin C: included to improve absorption and bioavailability.
What It’s Used For?
It’s specifically marketed to help with the emotional/behavioral symptoms associated with PMS, such as:
1. Anxiety or nervousness
2. Moodiness or gloominess
3. Stress
4. Irritability
What Research Exists on Oxaloacetate for PMS?
Clinical (Human) Trial Evidence
Depression symptoms reduced ~54%
Anxiety reduced ~51%
Perceived stress reduced ~36%
Aggression reduced ~18%
Suicidal-ideation components also improved almost ~48%
Limitations
Size: Only ~48 participants — relatively small for clinical research.
Scope: It focused mainly on mood symptoms, not physical PMS symptoms (like cramps, bloating).
Population: Excluded people with PMDD (a more severe mood disorder related to PMS) and clinical depression — so results don’t necessarily apply there.
Single supplement context: Results apply to the specific formulation studied (oxaloacetate plus vitamin C) — not every product on the market.
Funding and reporting: The study has been heavily promoted by the brand that sells the supplement, which can introduce bias even in peer-reviewed work, though the trial design itself was randomized and controlled.
Lifestyle Changes
Regular Exercise
Healthy Eating
Better Sleep & Stress Management
These are first things experts recommend because they help overall physical and emotional balance, not just PMS symptoms
Health & PMS–PMDD Awareness Statement
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